Immune Modulation of Vascular Resident Cells by Axl Orchestrates Carotid Intima-Media Thickening
نویسندگان
چکیده
منابع مشابه
Flow-induced vascular remodeling in the mouse: a model for carotid intima-media thickening.
OBJECTIVE Vascular remodeling of the carotid artery with intima-media thickness (IMT) is an important predictive factor for human cardiovascular disease. We characterized a mouse model of vascular remodeling. METHODS AND RESULTS The left external and internal carotid branches were ligated so that left carotid blood flow was reduced to flow via the occipital artery. In response to partial liga...
متن کاملComparison of Semi-Automated and Manual Measurements of Carotid Intima-Media Thickening
Carotid intima-media thickening (CIMT) is a marker of both arteriosclerotic and atherosclerotic risks. Technological advances have semiautomated CIMT image acquisition and quantification. Studies comparing manual and automated methods have yielded conflicting results possibly due to plaque inclusion in measurements. Low atherosclerotic risk subjects (n = 126) were recruited to minimise the effe...
متن کاملIs carotid artery intima-media thickening a reliable marker of early atherosclerosis?
BACKGROUND It is widely believed that carotid artery intima-media thickening represents an early marker for the development of atheroma. However, carotid intima-media thickening might also be expected to occur in response to an increased tensile stress and decreased wall shear stress which may accompany physical exercise. DESIGN, METHODS, AND RESULTS In order to test this hypothesis 24 athlet...
متن کاملdiurnal variations in blood pressure and their relation with carotid artery intima-media thickening
abstract introduction: hypertension is a very common cardiovascular disease with extensive effects on body organs. this study was conducted to compare the extent of target organ damage in hypertensive patients with and without significant nocturnal fall in blood pressure (dippers and non-dippers, respectively). methods: one-hundred patients with recently diagnosed hypertension underwent 24-hou...
متن کاملCarotid wall viscosity increase is related to intima-media thickening in hypertensive patients.
Increases in arterial wall viscosity and intima-media thickness (IMT) were found in hypertensive patients. Because smooth muscle cells are responsible for the viscous behavior of the arterial wall and they are involved in the process of thickening of the intima-media complex, this study evaluates the relationship between carotid thickness and wall viscosity. The simultaneous and noninvasive ass...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2012
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2012.01.036